Computational Systems Biology Group (CNB-CSIC)

Welcome to the web space of the Computational Systems Biology Group. We are integrated in the Systems Biology Program of the National Centre for Biotechnology (CNB-CSIC).

Use the links above to access the different sections.


  • Biology Methods and Protocols (BIOMAP) A new journal from Oxford University Press for publishing methodology and protocol papers in all areas of Biological Sciences, including Bioinformatics.
  • Last updates and changes


    ODCs server - Connections between rare diseases through shared genes and protein interactions


    MBROLE 2.0 server - Functional analysis of metabolomics data. New chemical and biological databases added, together with improved functionalities and interface


    Breaking-Cas server - gRNA design for CRISPR/Cas experiments for the ~700 eucaryotic genomes available in ENSEMBL through an interactive web interface. @BioinfoGP

    Review on Practical analysis of specificity-determining residues in protein families. Brief Bioinform. (2016) 17(2):255-61.

    © 2012, Computational Systems Biology Group. CNB-CSIC