Profiles, Motifs and Domains
Practical lessons
-
Profiles.
Protein Motifs and Domains
A selection of links
Databases of Protein Motifs, Domains and Families and tools.
-
Blocks. Multiple
alignments of
the most highly conserved regions of groups of proteins documented in
InterPro.
-
InterPro.
Integrated
view of commonly used motif databases.
-
MetaFam Protein Family
Database.
Comprehensive database of protein family information.
-
Motif. Scans sequences
to find
motifs, databases to find sequences that match profiles or patterns and
generates profiles from sequences provised by the user.
-
Pfam,
at
Sanger. Multiple sequence alignments and HMMs of protein domains
and
families, at Sanger Institute.
-
Pfam, at Saint Louis
-
Pfam, at Karolinska
-
Pfam, at INRA
-
PRINTS.
Database of groups of conserved motifs, or protein fingerprints.
-
ProDom.
Protein domain families automatically generated from SWISS-PROT and
TrEMBL.
-
PROSITE. Database of
protein
families and domains, defined by patterns and profiles, at ExPASy.
-
SMART. Simple
Modular
Architecture Research Tool, at EMBL.
June 2004
Michael Tress
Protein Design Group, CNB-CSIC.