Exercice I: Functional predictions based on interactions for mraZ (E coli hypothetical protein).

• Data & servers
  • Sequence. Database Acc: P22186; ID: MRAZ_ECOLI.
  • SRS server @EBI: Sequence retrieval system.
  • Blast server @NCBI (Sequence searches). For homology-based predictions.
  • STRING server @EMBL: Context-based predictions (gene neighbourhood, gene fusion, co-ocurrence, co-expression, text-mining, etc. -see theoretical part-).
  • ECID @CNB: E coli predicted interactions databaase (i2h, mirrortree, phylogenetic profiles,gene neighbourhood, gene fusion -see theoretical part-).

• Some results
  • SwissProt file (local).
  • BLAST results (local).
  • STRING results (local).

• Additional Resources
  • Experimental protein interactions databases (D. Juan, CNB).
  • Other databases of predicted protein interactions (D. Juan, CNB).

Exercice II:Context information for SBDS protein

• Are you in agreement with the blinking sentence of this Paper?
• Look for context information about this protein in STRING. (local copy of the results).