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3.2 Sheets
3.2.4 Bulges
Another irregularity found in antiparallel beta sheets is the hydrogen-bonding
of two residues from one strand with one residue from the other called
a beta bulge. Bulges are most often found in antiparallel sheets with ~5%
of bulges occurring in parallel strands (Richardson, 1981). Bulges, like
"Turns" effect the directionality of
the polypeptide chain and classical ones, like the one shown in Figure
13 also accentuate the right-handed twist of the sheet.
Figure 13. A classical beta-bulge in chymotrypsin
(1CHG.PDB) involving residues 33 and 41-42. Hydrogen bonds are indicated
with dotted lines connecting the donor and acceptor atoms.
download 1CHG.PDB
download RasMol script
No Title - 31 MAY 96
written by Kurt D. Berndt
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