Four options are available to stop the growing of the tree:
Unrestricted Grow
The tree will grow until all different sequences are splitted.
Resource Threshold
The resource in a node (i.e. a leaf of the tree) is the mean distance between each sequence and this node. If the resource in a node does not reach this threshold, this node does not split any more
Variability Threshold (abs.)
The variability in a node (i.e. a leaf of the tree) is the maximum distance among all the sequences in this node. If the variability in a node does not reach this threshold, this node does not split anymore
Variability Threshold (%)
The variability in a node (i.e. a leaf of the tree) is the maximum distance among all the sequences in this node. If the variability in a node does not reach this threshold, this node does not split anymore
See (Herrero et al.2001) for details on the calculation of the threshold.
Maximum number of cycles (Advanced mode)
Additionaly, you can force the end of the trining after a certain number of cycles. Each cycle corresponds to a division of a node.
Herrero, J., Valencia, A. and Dopazo, J. (2001) A hierarchical unsupervised growing neural network for clustering gene expression patterns. Bioinformatics.17:126-136
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Last rev. March 16th, 2001